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Intravitreal anti-vascular endothelial growth factor agents as an adjunct in the management of Coats' disease in children.
[coats disease]
We
describe
the
role
of
intravitreal
anti-
vascular
endothelial
growth
factor
(
VEGF
)
agents
in
Coats
'
disease
in
children
.
In
a
prospective
,
interventional
,
non-randomized
case
series
,
three
patients
(
three
eyes
)
aged
16
,
seven
and
two
years
were
diagnosed
to
have
Coats
'
disease
.
In
Case
1
(
16
yr
/
male
)
with
macular
edema
,
previous
laser
photocoagulation
being
unsuccessful
,
intravitreal
pegaptanib
sodium
(
Macugen
)
was
tried
.
Case
2
(
seven
yr
/
male
)
and
Case
3
(
two
yr
/
female
)
were
diagnosed
to
have
Stage
4
Coats
'
and
underwent
external
needle
drainage
,
laser
photocoagulation
,
SF
6
gas
injection
and
intravitreal
injection
of
bevacizumab
(
Avastin
)
.
Reduction
of
exudation
and
attached
posterior
pole
(
Cases
2
and
3
)
was
seen
at
a
follow-up
of
six
months
and
two
months
respectively
.
Intravitreal
anti-
VEGF
agents
may
be
successfully
used
as
adjunct
treatment
in
select
cases
of
Coats
'
disease
in
childhood
.
Diseases
Validation
Diseases presenting
"attached posterior pole (cases"
symptom
coats disease
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