Rare Diseases Symptoms Automatic Extraction
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Intravitreal anti-vascular endothelial growth factor agents as an adjunct in the management of Coats' disease in children.
[coats disease]
We
describe
the
role
of
intravitreal
anti-
vascular
endothelial
growth
factor
(
VEGF
)
agents
in
Coats
'
disease
in
children
.
In
a
prospective
,
interventional
,
non-randomized
case
series
,
three
patients
(
three
eyes
)
aged
16
,
seven
and
two
years
were
diagnosed
to
have
Coats
'
disease
.
In
Case
1
(
16
yr
/
male
)
with
macular
edema
,
previous
laser
photocoagulation
being
unsuccessful
,
intravitreal
pegaptanib
sodium
(
Macugen
)
was
tried
.
Case
2
(
seven
yr
/
male
)
and
Case
3
(
two
yr
/
female
)
were
diagnosed
to
have
Stage
4
Coats
'
and
underwent
external
needle
drainage
,
laser
photocoagulation
,
SF
6
gas
injection
and
intravitreal
injection
of
bevacizumab
(
Avastin
)
.
Reduction
of
exudation
and
attached
posterior
pole
(
Cases
2
and
3
)
was
seen
at
a
follow-up
of
six
months
and
two
months
respectively
.
Intravitreal
anti-
VEGF
agents
may
be
successfully
used
as
adjunct
treatment
in
select
cases
of
Coats
'
disease
in
childhood
.
Diseases
Validation
Diseases presenting
"edema"
symptom
acute rheumatic fever
adrenomyeloneuropathy
aniridia
cadasil
canavan disease
classical phenylketonuria
coats disease
congenital toxoplasmosis
cushing syndrome
cutaneous mastocytosis
erythropoietic protoporphyria
esophageal carcinoma
fabry disease
familial mediterranean fever
focal myositis
harlequin ichthyosis
homocystinuria without methylmalonic aciduria
inclusion body myositis
lamellar ichthyosis
liposarcoma
lymphangioleiomyomatosis
malignant atrophic papulosis
pleomorphic liposarcoma
systemic capillary leak syndrome
trochlear dysplasia
von hippel-lindau disease
waldenström macroglobulinemia
This symptom has already been validated
