[Coats disease].

[coats disease]

Coats disease is characterized by idiopathic congenital retinal telangiectasis and exudative retinopathy . Mostly young males are affected . The disease is usually unilateral . Visual prognosis varies from full visual acuity to blindness according to the extent of retinal exudation . Retinoblastoma is a major differential diagnosis particularly in small children but other causes of exudative retinopathy must also be considered . Treatment aims include obliteration of the telangiectasis in order to resolve retinal exudation and achieve reattachment of the retina . Therapeutic options comprise laser coagulation or cryotherapy , drainage of subretinal fluid , buckling surgery and pars plana vitrectomy . In more advanced cases with therapy-resistant secondary glaucoma enucleation may be required . More recently , intravitreal administration of VEGF inhibitors has become an option .