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[Analysis of changes of ultrasonic image and hemodynamics of retrobulbar blood vessels in Coats disease].
[coats disease]
To
analyze
the
changes
of
color
Doppler
flow
imaging
(
CDFI
)
and
hemodynamics
of
retrobulbar
blood
vessels
in
Coats
disease
.
It
was
a
prospective
and
self-comparative
study
in
which
18
cases
(
18
eyes
)
were
included
.
Axial
eye
length
was
measured
with
A
scan
.
Routine
CDFI
was
performed
in
all
cases
.
We
examined
ophthalmic
arteries
(
OA
)
,
central
retinal
arteries
(
CRA
)
and
posterior
ciliary
arteries
(
PCA
)
by
CDFI
,
and
recorded
the
peak
systolic
velocities
(
PSV
)
,
end
diastolic
velocities
(
EDV
)
,
time
averaged
maximum
velocities
(
TAMX
)
,
pulsatility
indexes
(
PI
)
and
resistance
indexes
(
RI
)
in
all
cases
.
Each
hemodynamic
parameter
in
the
affected
eye
(
21
.
36
±
1
.
19
)
mm
was
compared
with
those
in
the
contralateral
normal
eye
(
controls
)
.
T
-
test
was
used
for
the
estimation
of
significance
of
the
difference
between
the
diseased
and
normal
eyes
.
The
axial
length
in
diseased
eyes
was
significantly
shorter
than
that
of
the
controls
(
22
.
92
±
1
.
09
)
mm
(
t
=
3
.
617
,
P
<
0
.
05
)
.
The
changes
of
CDFI
in
diseased
eyes
included
retinal
detachment
,
retinal
cyst
,
subretinal
organization
,
etc
.
Vitreoretinal
traction
,
intraocular
ossification
and
calcification
were
uncommon
.
The
PSV
(
6
.
96
±
1
.
21
)
cm
/
s
and
EDV
(
1
.
99
±
0
.
36
)
cm
/
s
in
the
diseased
eyes
were
significantly
lower
than
the
PSV
(
8
.
30
±
1
.
46
)
cm
/
s
and
EDV
(
2
.
48
±
0
.
47
)
cm
/
s
in
the
control
eyes
(
t
=
2
.
995
,
3
.
476
;
P
<
0
.
05
)
.
No
significance
difference
was
present
in
other
hemodynamic
parameters
between
diseased
and
normal
eyes
.
Coats
disease
is
a
congenital
disease
that
may
influence
the
development
of
the
eye
.
The
ultrasonography
is
helpful
for
the
diagnosis
and
differential
diagnosis
in
Coats
disease
.
Low
perfusion
of
the
central
optic
artery
might
exist
in
Coats
disease
.
The
hemodynamics
changes
in
Coats
disease
require
further
studies
.
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