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A random Abstract
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The continuum of primary retinal telangiectasia.
[coats disease]
Primary
retinal
telangiectasia
is
characterized
by
abnormalities
in
the
retinal
vasculature
.
Any
alteration
of
the
normal
retinal
vasculature
may
result
in
variable
degrees
of
retinal
leakage
,
hemorrhages
,
and
exudates
.
The
retinal
telangiectatic
conditions
of
Coats
'
disease
,
Leber
's
miliary
aneurysms
,
and
idiopathic
macular
telangiectasia
(
IMT
)
,
although
historically
considered
separate
entities
,
may
in
fact
be
variants
of
the
same
pathophysiologic
vascular
process
.
This
is
based
on
observations
noting
that
they
share
similarities
in
pathogenesis
,
histology
,
and
clinical
presentation
.
These
observations
are
controversial
and
are
contested
in
the
literature
.
Conversely
,
others
have
documented
Coats
'
disease
,
Leber
's
miliary
aneurysms
,
and
IMT
as
unique
and
separate
retinal
conditions
,
each
with
specific
features
.
Three
cases
are
presented
spanning
the
spectrum
of
primary
retinal
telangiectasia
.
Clinical
evaluation
,
dilated
fundus
examination
,
and
auxiliary
testing
document
both
the
similar
characteristics
that
the
entities
share
as
well
as
the
distinct
features
,
which
define
each
disease
's
nomenclature
and
categorization
.
Coats
'
disease
,
Leber
's
miliary
aneurysms
,
and
IMT
may
be
part
of
a
singular
clinical
spectrum
sharing
pathophysiologic
and
histopathologic
features
and
similarities
in
clinical
presentation
.
Diseases
Validation
Diseases presenting
"normal retinal vasculature"
symptom
coats disease
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