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A combination of intravitreal bevacizumab injection with tunable argon yellow laser photocoagulation as a treatment for adult-onset Coats' disease.
[coats disease]
The
purpose
of
this
study
was
to
investigate
the
effectiveness
of
intravitreal
bevacizumab
injections
combined
with
tunable
argon
yellow
laser
photocoagulation
as
a
treatment
for
adult-onset
Coats
'
disease
.
We
consecutively
treated
3
patients
suffering
from
Coats
'
disease
diagnosed
in
adulthood
with
a
combination
of
intravitreal
bevacizumab
injection
and
tunable
argon
yellow
laser
photocoagulation
.
All
patients
received
an
intravitreal
injection
of
2
.
5
mg
bevacizumab
together
with
various
sessions
of
laser
photocoagulation
targeting
the
area
of
telangiectasia
.
The
patients
'
best-corrected
visual
acuities
were
recorded
.
Fundus
photography
,
fluorescein
angiography
(
FA
)
,
and
optical
coherence
tomography
were
used
to
monitor
vascular
and
retinal
exudate
changes
.
Fundus
photography
and
FA
of
all
3
patients
revealed
significant
regression
of
the
vascular
dilatation
and
the
aneurysmal
appearance
of
the
telangiectasia
areas
.
Optical
coherence
tomography
also
showed
a
significant
subsidence
of
the
macular
edema
and
submacular
fluid
in
all
patients
.
A
concomitant
improvement
in
visual
acuity
was
also
noted
.
No
treatment-related
complications
were
identified
.
Combining
intravitreal
bevacizumab
and
tunable
argon
yellow
laser
photocoagulation
is
an
efficient
treatment
of
choice
for
Coats
'
disease
that
has
been
diagnosed
in
adulthood
.
Diseases
Validation
Diseases presenting
"edema"
symptom
acute rheumatic fever
adrenomyeloneuropathy
aniridia
cadasil
canavan disease
classical phenylketonuria
coats disease
congenital toxoplasmosis
cushing syndrome
cutaneous mastocytosis
erythropoietic protoporphyria
esophageal carcinoma
fabry disease
familial mediterranean fever
focal myositis
harlequin ichthyosis
homocystinuria without methylmalonic aciduria
inclusion body myositis
lamellar ichthyosis
liposarcoma
lymphangioleiomyomatosis
malignant atrophic papulosis
pleomorphic liposarcoma
systemic capillary leak syndrome
trochlear dysplasia
von hippel-lindau disease
waldenström macroglobulinemia
This symptom has already been validated
