Peripheral retinal nonperfusion in fellow eyes in coats disease.

[coats disease]

To measure peripheral nonperfusion and describe bilateral vascular abnormalities in patients with Coats disease , emphasizing subtle findings in the contralateral eyes of patients diagnosed with unilateral disease .Clinical records , including retina drawings and fluorescein angiography images obtained under anesthesia , were retrospectively reviewed from consecutive pediatric patients with Coats disease . The main outcome measure was disk diameters of peripheral nonperfusion and proportion of Coats disease patients with bilateral findings .Twenty -two of 32 patients with Coats disease had bilateral abnormal peripheral vasculature . In Group 1 (classic Coats disease : presumed unilateral , ocular only disease ), 15 of 24 patients had peripheral nonperfusion >2 disk diameters in their contralateral eyes , 5 with telangiectasis and /or microaneurysms . Seven of 8 patients in Group 2 (Coats-like disease : systemic and /or clinically bilateral disease ) had bilateral vascular anomalies .Bilateral vascular abnormalities are more common in Coats disease than previously reported . This observation supports a systemic and /or genetic association with Coats disease . Patients with Coats disease should have careful evaluation of the periphery of the less affected eye , preferably with fluorescein angiography , to identify vascular changes not visible clinically . Both eyes warrant surveillance over the lifetime of the patient for potential progression to exudative disease that would warrant treatment .