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Effect of L-dopa on visual evoked potentials and neuropsychological tests in adult phenylketonuria patients.
[classical phenylketonuria]
Eight
adult
,
untreated
patients
with
classical
phenylketonuria
received
L-
dopa
and
a
decarboxylase
inhibitor
for
2
weeks
.
No
effect
of
L-
dopa
therapy
on
choice
reaction
time
tasks
,
sustained
attention
,
frontal
lobal
function
as
well
as
latencies
of
visual
evoked
potentials
was
found
.
The
results
raise
the
question
if
adult
patients
with
phenylketonuria
really
suffer
from
functional
dopamine
deficiency
.