Rare Diseases Symptoms Automatic Extraction
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A random Abstract
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Outcomes in biliary malignancy.
[cholangiocarcinoma]
The
biliary
malignancies
that
are
reviewed
here
are
gallbladder
cancer
(
GBC
)
,
intrahepatic
cholangiocarcinoma
(
IHC
)
,
and
perihilar
cholangiocarcinoma
(
PHC
)
.
The
focus
is
on
outcomes
after
potentially
curative
resection
of
biliary
malignancies
.
Key
outcomes
are
postoperative
mortality
,
median
and
5
-
year
overall
survival
(
OS
)
,
recurrence-free
survival
,
and
recurrence
patterns
.
Poor
prognostic
factors
for
recurrence
and
survival
as
well
as
prognostic
models
are
also
discussed
.
The
incidence
of
biliary
malignancies
in
the
United
States
is
about
5
in
100
,
000
.
Postoperative
mortality
for
resection
of
GBC
and
IHC
is
similar
to
that
of
liver
resections
for
other
indications
.
However
,
90
day
postoperative
mortality
after
liver
resection
for
PHC
is
about
10
%
.
For
GBC
,
median
OS
depends
strongly
on
the
T
-
stage
and
ranges
from
8
months
(
pT
3
)
to
79
months
(
pT
1
b
)
.
Median
OS
after
resection
for
IHC
is
about
30
months
,
and
for
PHC
about
38
months
.
The
majority
of
patients
with
biliary
malignancies
develop
a
recurrence
after
resection
.
Patients
with
GBC
recur
early
with
a
median
time
to
recurrence
of
12
months
,
versus
about
20
months
for
IHC
and
PHC
.
In
patients
with
resected
IHC
or
PHC
locoregional
recurrence
was
the
only
site
of
recurrence
in
about
60
%
of
patients
,
versus
15
%
in
patients
with
GBC
.
Poor
prognostic
factors
after
resection
of
all
biliary
malignancies
include
the
presence
of
lymph
node
metastasis
,
a
positive
surgical
resection
margin
,
and
moderate
or
poor
tumor
differentiation
.
Several
prognostic
nomograms
have
been
developed
to
predict
long
-term
outcomes
of
biliary
cancer
resection
.
Diseases
Validation
Diseases presenting
"cancer"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
alpha-thalassemia
benign recurrent intrahepatic cholestasis
cadasil
canavan disease
carcinoma of the gallbladder
cholangiocarcinoma
coats disease
congenital adrenal hyperplasia
congenital diaphragmatic hernia
cowden syndrome
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
erdheim-chester disease
erythropoietic protoporphyria
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
familial mediterranean fever
gm1 gangliosidosis
heparin-induced thrombocytopenia
hereditary cerebral hemorrhage with amyloidosis
hirschsprung disease
hodgkin lymphoma, classical
inclusion body myositis
junctional epidermolysis bullosa
kabuki syndrome
kallmann syndrome
kindler syndrome
lamellar ichthyosis
liposarcoma
locked-in syndrome
lymphangioleiomyomatosis
monosomy 21
neuralgic amyotrophy
oculocutaneous albinism
oligodontia
oral submucous fibrosis
papillon-lefèvre syndrome
pendred syndrome
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
pyruvate dehydrogenase deficiency
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
This symptom has already been validated