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Cholangiocarcinoma in a middle-aged patient working at a printing plant.
[cholangiocarcinoma]
A
39
-
year
-old
male
with
elevated
serum
transferases
consulted
our
hospital
in
September
2010
.
Since
1999
,
he
had
worked
at
a
printing
company
using
organic
solvents
.
Cholangiography
revealed
stenosis
of
the
left
hepatic
duct
with
peripheral
dilation
,
stricture
of
the
right
hepatic
duct
,
and
irregularity
of
the
extrahepatic
bile
duct
.
As
a
preoperative
diagnosis
of
sclerosing
cholangitis
and
cholangiocarcinoma
was
made
,
extended
left
hepatectomy
with
resection
of
the
extrahepatic
bile
duct
and
anastomosis
of
the
anterior
and
posterior
branches
of
the
bile
duct
and
the
jejunum
(
Roux-en
Y
reconstruction
)
were
performed
.
A
histological
examination
showed
papillary
carcinoma
of
the
medial
hepatic
bile
duct
with
intraductal
growth
,
and
biliary
intraepithelial
neoplasia
-
2
/
3
lesions
from
the
medial
hepatic
bile
duct
to
the
right
hepatic
and
the
common
bile
ducts
.
Chronic
cholangitis
was
shown
around
the
tumors
.
Postoperatively
,
the
patient
was
treated
with
adjuvant
chemo-radiation
,
and
he
is
doing
well
30
months
after
the
operation
,
without
recurrence
.
Unknown
causes
,
including
exposure
to
organic
solvents
,
might
have
induced
chronic
bile
duct
injury
and
contributed
to
the
development
of
cholangiocarcinoma
.
Diseases
Validation
Diseases presenting
"hepatic duct"
symptom
cholangiocarcinoma
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