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Cholangiocarcinoma in a middle-aged patient working at a printing plant.
[cholangiocarcinoma]
A
39
-
year
-old
male
with
elevated
serum
transferases
consulted
our
hospital
in
September
2010
.
Since
1999
,
he
had
worked
at
a
printing
company
using
organic
solvents
.
Cholangiography
revealed
stenosis
of
the
left
hepatic
duct
with
peripheral
dilation
,
stricture
of
the
right
hepatic
duct
,
and
irregularity
of
the
extrahepatic
bile
duct
.
As
a
preoperative
diagnosis
of
sclerosing
cholangitis
and
cholangiocarcinoma
was
made
,
extended
left
hepatectomy
with
resection
of
the
extrahepatic
bile
duct
and
anastomosis
of
the
anterior
and
posterior
branches
of
the
bile
duct
and
the
jejunum
(
Roux-en
Y
reconstruction
)
were
performed
.
A
histological
examination
showed
papillary
carcinoma
of
the
medial
hepatic
bile
duct
with
intraductal
growth
,
and
biliary
intraepithelial
neoplasia
-
2
/
3
lesions
from
the
medial
hepatic
bile
duct
to
the
right
hepatic
and
the
common
bile
ducts
.
Chronic
cholangitis
was
shown
around
the
tumors
.
Postoperatively
,
the
patient
was
treated
with
adjuvant
chemo-radiation
,
and
he
is
doing
well
30
months
after
the
operation
,
without
recurrence
.
Unknown
causes
,
including
exposure
to
organic
solvents
,
might
have
induced
chronic
bile
duct
injury
and
contributed
to
the
development
of
cholangiocarcinoma
.
Diseases
Validation
Diseases presenting
"neoplasia"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
aniridia
carcinoma of the gallbladder
cholangiocarcinoma
cowden syndrome
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dentin dysplasia
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
hodgkin lymphoma, classical
liposarcoma
lymphangioleiomyomatosis
neuralgic amyotrophy
oligodontia
oral submucous fibrosis
pleomorphic liposarcoma
primary effusion lymphoma
pyomyositis
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wolf-hirschhorn syndrome
This symptom has already been validated