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What is the Incidence of Biliary Carcinoma in Choledochal Cysts, When Do They Develop, and How Should it Affect Management?
[cholangiocarcinoma]
The
incidence
of
cancer
in
choledochal
cysts
(
CCs
)
in
adults
was
calculated
to
determine
the
timing
and
need
for
surgery
.
In
78
publications
(
1996
-
2010
)
,
434
of
5780
reported
CCs
patients
had
cancer
.
Cholangiocarcinoma
(
70
.
4
Â
%
)
and
gallbladder
cancer
(
23
.
5
Â
%
)
were
the
most
common
malignancies
.
Only
nine
malignancies
were
reported
before
age
18
(
0
.
42
Â
%
)
.
In
contrast
,
the
incidence
of
malignancy
in
adults
was
11
.
4
Â
%
.
The
median
age
for
diagnosis
of
cancer
was
42
Â
years
,
and
the
incidence
increased
with
each
decade
.
