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A retrospective and comparative study of inflammatory myofibroblastic tumor of the liver.
[cholangiocarcinoma]
Inflammatory
myofibroblastic
tumor
of
the
liver
(
IMTL
)
is
a
very
rare
benign
disease
with
a
good
prognosis
.
To
determine
the
clinical
,
radiological
,
and
pathological
characteristics
of
IMTL
.
The
diagnosis
and
treatment
strategies
were
discussed
.
A
total
of
eleven
patients
with
pathologically
confirmed
IMTL
receiving
treatment
over
a
15
-
year
period
were
reviewed
retrospectively
.
The
analysis
included
demographics
information
and
pertinent
clinical
data
.
Results
were
compared
that
obtained
from
patients
with
hepatocellular
carcinoma
(
HCC
)
,
intrahepatic
cholangiocarcinoma
(
IHCC
)
and
,
metastatic
liver
cancer
(
MLC
)
receiving
surgical
resection
.
In
comparison
to
HCC
,
IHCC
,
and
MLC
,
IMTL
has
an
earlier
onset
(
P
<
0
.
001
)
.
IMTL
patients
had
significantly
lower
AST
(
P
=
0
.
003
)
and
higher
ALP
(
P
=
0
.
034
)
than
HCC
patients
,
and
higher
GGT
(
P
=
0
.
010
)
than
MLC
patients
.
Increased
serum
alpha-fetoprotein
(
AFP
)
level
was
detected
in
only
one
patient
.
Serum
AFP
was
significantly
lower
in
patients
with
IMTL
(
P
=
0
.
000
)
than
in
those
with
HCC
but
not
IHCC
(
P
=
0
.
558
)
or
MLC
(
P
=
0
.
514
)
.
In
contrast
to
elevated
serum
CA
1
9
-
9
in
patients
with
HCC
/
IHCC
/
MLC
,
the
serum
CA
1
9
-
9
in
IMTL
cases
was
generally
normal
(
vs
.
HCC
P
=
0
.
008
;
vs
.
IHCC
P
=
0
.
000
;
vs
.
MLC
P
=
0
.
022
)
.
In
9
IMTL
patients
,
the
tumor
appeared
as
a
hypoechogenic
solid
mass
on
the
ultrasonography
.
In
contrast
,
most
patients
with
HCC
,
IHCC
,
or
MLC
showed
hybrid
echo
.
In
contrast
CT
and
MRI
,
the
lesion
of
IMTL
and
MLC
appeared
as
peripheral
enhancement
.
Lab
tests
,
imaging
features
,
and
patient
history
are
helpful
in
differential
diagnosis
of
IMTL
from
HCC
/
IHCC
/
MLC
.
Surgical
resection
is
curative
for
IMTL
.
Diseases
Validation
Diseases presenting
"elevated serum"
symptom
adrenomyeloneuropathy
allergic bronchopulmonary aspergillosis
aromatase deficiency
cholangiocarcinoma
congenital adrenal hyperplasia
cushing syndrome
familial hypocalciuric hypercalcemia
omenn syndrome
pleomorphic liposarcoma
scrub typhus
x-linked adrenoleukodystrophy
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