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Microscopic identification of possible Clonorchis/Opisthorchis infection in two Ghanaian women with undiagnosed abdominal discomfort: two case reports.
[cholangiocarcinoma]
The
impact
of
foodborne
trematode
infections
is
gaining
recognition
worldwide
.
Clonorchiasis
and
opisthorchiasis
are
some
of
the
most
neglected
tropical
foodborne
diseases
that
pose
a
significant
threat
to
human
health
.
Persistent
or
chronic
infection
of
Clonorchis
/
Opisthorchis
often
leads
to
hepatobiliary
diseases
including
cholangitis
,
cholelithiasis
,
cholecystitis
,
pancreatitis
,
hepatic
fibrosis
,
cholangiocarcinoma
and
liver
cancer
.
Two
cases
of
Clonorchis
/
Opisthorchis
infection
in
humans
in
the
Central
Region
of
Ghana
are
reported
.
Eggs
suspected
to
be
from
Clonorchis
sinensis
or
Opisthorchis
species
were
detected
in
the
stools
of
a
29
-
year
-old
Ghanaian
woman
and
an
18
-
year
-old
Ghanaian
woman
in
two
clinics
in
the
Central
Region
of
Ghana
.
The
diagnosis
was
based
on
clinical
symptoms
as
well
as
detection
of
the
eggs
of
the
trematode
in
the
faeces
of
the
patients
using
light
microscopy
after
staining
with
Giemsa
or
Ziehl-
Neelsen
stains
.
To
the
best
of
our
knowledge
these
are
the
first
documented
cases
of
Clonorchis
sinensis
or
Opisthorchis
species
infection
in
Ghana
.
The
detection
of
this
infection
in
these
patients
in
Ghana
should
be
of
concern
to
clinicians
because
the
infection
can
be
easily
misdiagnosed
since
the
accompanying
clinical
symptoms
are
malaria
-like
.
Consideration
should
therefore
be
given
to
Clonorchis
sinensis
and
Opisthorchis
species
when
diagnosing
patients
presenting
with
malaria
-like
symptoms
.
Diseases
Validation
Diseases presenting
"chronic infection"
symptom
acute rheumatic fever
carcinoma of the gallbladder
cholangiocarcinoma
congenital toxoplasmosis
dentin dysplasia
lamellar ichthyosis
papillon-lefèvre syndrome
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