IgA-dominant Postinfectious Glomerulonephritis Associated with Escherichia coli Infection Caused by Cholangitis.

[cholangiocarcinoma]

A 76 -year -old man with a history of type 2 diabetes mellitus was admitted with cholangitis caused by cholangiocarcinoma . Cholangitis with Escherichia coli (E . coli ) bacteremia recurred due to the unstable bile drainage . At 1 month after recurrence , rapidly progressive glomerulonephritis with nephrotic syndrome was manifested . Renal biopsy findings were consistent with immunoglobulin A (IgA )-dominant postinfectious glomerulonephritis (PIGN ). After ensuring that the recurrent cholangitis was controlled by drainage and antibiotic therapy , oral prednisolone was initiated , and the patient 's renal function and proteinuria subsequently gradually improved . This is the first case report of IgA-dominant PIGN associated with cholangitis caused by E . coli infection .