Intraductal papillary neoplasm of the bile duct developing in a patient with primary sclerosing cholangitis: A case report.

[cholangiocarcinoma]

We report a case of intraductal papillary neoplasm of the bile duct (IPNB ) that developed in a patient with primary sclerosing cholangitis . A 46 -year -old woman was admitted to our hospital with obstructive jaundice . The liver function tests demonstrated increased serum liver enzyme levels . Computed tomography showed dilatation of the intrahepatic bile ducts . Abdominal ultrasonography revealed a highly echoic protruding lesion in the posterior bile duct near the right lobe of the liver . The lesion was suspected to be IPNB , but we were unable to confirm whether it was a carcinoma . A right hepatectomy was performed , and this showed that the dilated bile duct was filled with mucin and contained several yellowish papillary tumors . Histologically , the neoplastic biliary epithelium showed papillary growth in the dilated lumen . The tumor was diagnosed as IPNB , high -grade intraepithelial neoplasia secreting abundant mucin . No recurrence has been detected 3 years after surgery .

Diseases
Validation

Diseases presenting "neoplasia" symptom

achondroplasia

acute rheumatic fever

adrenal incidentaloma

aniridia

carcinoma of the gallbladder

cholangiocarcinoma

cowden syndrome

cushing syndrome

cutaneous mastocytosis

dedifferentiated liposarcoma

dentin dysplasia

dystrophic epidermolysis bullosa

epidermolysis bullosa simplex

esophageal adenocarcinoma

esophageal carcinoma

esophageal squamous cell carcinoma

familial hypocalciuric hypercalcemia

hodgkin lymphoma, classical

liposarcoma

lymphangioleiomyomatosis

neuralgic amyotrophy

oligodontia

oral submucous fibrosis

pleomorphic liposarcoma

primary effusion lymphoma

pyomyositis

von hippel-lindau disease

waldenström macroglobulinemia

well-differentiated liposarcoma

werner syndrome

wolf-hirschhorn syndrome

This symptom has already been validated