Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Genetic and environmental determinants of risk for cholangiocarcinoma in Thailand.
[cholangiocarcinoma]
Cholangiocarcinoma
(
CCA
)
is
a
difficult
cancer
to
diagnose
in
the
early
stage
and
to
treat
by
curative
resection
.
The
incidence
of
CCA
in
the
northeast
of
Thailand
is
the
highest
in
the
world
.
To
make
progress
in
detecting
a
high
risk
group
and
in
the
prevention
and
detection
of
CCA
,
we
have
been
analyzing
the
risk
factors
for
CCA
.
Although
liver
fluke
infection
is
known
to
be
a
risk
factor
,
there
are
patients
who
are
not
infected
with
the
liver
fluke
and
not
all
people
infected
with
the
liver
fluke
will
suffer
from
the
disease
.
Therefore
,
it
is
of
the
utmost
importance
to
analyze
the
risk
factors
and
the
mechanism
to
prevent
the
disease
and
also
to
detect
the
disease
in
its
early
stage
to
save
patients
'
lives
.
Through
collaboration
among
Thai
and
Japanese
researchers
,
we
analyzed
the
genetic
and
environmental
determinants
of
risks
for
CCA
.
Also
,
we
have
been
trying
to
develop
methods
to
detect
the
disease
in
a
non-invasive
way
.
Without
repeating
findings
reported
in
various
reviews
on
CCA
,
we
will
first
discuss
the
environmental
and
genetic
determinants
of
the
risks
for
CCA
.
Second
,
we
will
discuss
the
properties
of
CCA
,
including
the
etiological
agents
and
the
mechanism
of
cholangiocarcinogenesis
,
and
finally
,
we
will
discuss
future
approaches
to
prevent
and
cure
CCA
from
the
standpoint
of
evidence-based
medicine
.
We
will
discuss
these
points
by
including
the
data
from
our
laboratories
.
We
would
like
to
emphasize
the
importance
of
the
genetic
data
,
especially
whole
genome
approaches
,
to
understand
the
properties
of
CCA
,
to
find
a
high
risk
population
for
CCA
and
to
develop
effective
preventative
methods
to
stop
the
carcinogenic
steps
toward
CCA
in
the
near
future
.
In
addition
,
it
is
of
the
upmost
importance
to
develop
a
non-invasive
,
specific
and
sensitive
method
to
detect
CCA
in
its
early
stage
for
the
application
of
modern
medical
approaches
to
help
patients
with
CCA
.
Diseases
Validation
Diseases presenting
"to understand the properties of cca"
symptom
cholangiocarcinoma
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom