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Whole-body magnetic resonance imaging: an essential tool for diagnosis and work up of non-oncological systemic diseases in children.
[child syndrome]
Whole-body
MRI
(
WBMRI
)
is
a
non-irradiating
imaging
technique
,
suitable
to
investigate
the
extent
of
multisystemic
diseases
in
pediatric
patients
.
However
its
real
impact
on
diagnosis
and
management
of
non-oncological
pediatric
diseases
remains
unclear
.
We
present
our
experience
of
pediatric
WBMRI
in
various
pathologies
.
We
retrospectively
reviewed
medical
files
of
all
non-
oncologic
patients
who
underwent
WBMRI
from
January
2008
to
November
2012
.
The
MRI
protocol
included
T
1
weighted
and
3
D
SPACE
Inversion
Recovery
(
IR
)
and
fat
saturated
diffusion
weighted
(
DWI
)
sequence
.
We
reviewed
medical
records
in
order
to
determine
if
performing
WBMRI
added
useful
information
for
diagnostic
purposes
and
/
or
changed
clinical
management
.
Forty
-
two
children
were
included
in
the
study
(
19
F
,
23
M
)
(
median
age
4
.
7
years
)
.
Twenty
-
one
children
underwent
general
anesthesia
.
WBMRI
was
a
useful
tool
to
provide
correct
diagnosis
in
chronic
recurrent
multifocal
osteomyelitis
(
CRMO
)
,
and
to
identify
the
origin
of
fever
or
arthralgia
of
unknown
etiology
.
WBMRI
allowed
to
determine
the
extent
of
disease
in
juvenile
idiopathic
arthritis
(
JIA
)
,
chronic
granulomatous
disorder
,
enchondromatosis
,
Langerhans
cell
histiocytosis
,
and
in
the
assessment
of
tumor
burden
in
neurofibromatosis
type
I
.
For
the
battered
child
syndrome
,
the
influence
on
management
was
rather
minimal
.
For
each
of
these
pathologies
we
performed
a
review
of
recent
literature
.
WBMRI
is
easy
to
perform
in
children
and
allows
the
assessment
of
systemic
diseases
or
discovery
of
lesions
ignored
by
clinical
examination
.
WBMRI
influenced
the
decisional
process
and
clinical
management
of
various
pathologies
in
our
series
.
