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Bullous pemphigoid as a dermadrome associated with spindle cell carcinoma of the gallbladder.
[carcinoma of the gallbladder]
Skin
disorders
that
appear
in
association
with
internal
malignancies
are
called
dermadromes
.
Bullous
pemphigoid
(
BP
)
,
which
is
a
major
autoimmune
disease
of
the
skin
,
is
considered
to
be
a
dermadrome
,
although
there
have
been
conflicting
reports
.
We
report
a
case
of
BP
that
preceded
the
diagnosis
of
an
internal
malignancy
.
Although
we
could
not
detect
any
malignancies
on
chest
,
abdominal
or
pelvic
computer
tomography
on
the
first
hospital
admission
,
intensive
screening
on
the
third
admission
revealed
a
gallbladder
malignancy
.
Laparoscopic
cholecystectomy
was
performed
.
Histopathology
showed
a
spindle
cell
carcinoma
of
the
gallbladder
.
To
the
best
of
our
knowledge
,
this
is
the
first
report
of
a
spindle
cell
carcinoma
of
the
gallbladder
in
a
patient
with
BP
.
Diseases
Validation
Diseases presenting
"autoimmune disease of the skin"
symptom
carcinoma of the gallbladder
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