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Cushing's syndrome caused by an ACTH-producing large cell neuroendocrine carcinoma of the gallbladder.
[carcinoma of the gallbladder]
Malignancies
of
the
gallbladder
,
including
neuroendocrine
tumors
,
are
uncommon
,
mostly
found
incidentally
after
cholecystectomy
and
are
frequently
asymptomatic
in
the
early
stages
,
but
highly
fatal
.
Limited
data
is
available
on
adrenocorticotropic
hormone
(
ACTH
)
-
producing
neuroendocrine
tumors
specifically
originating
from
the
gallbladder
.
We
report
the
clinical
and
radiographic
findings
,
which
included
positron
emission
tomography
and
computed
tomography
,
of
a
patient
with
a
gallbladder
mass
who
presented
with
Cushing
's
syndrome
.
Subsequently
,
a
diagnosis
of
ACTH-producing
large
cell
neuroendocrine
carcinoma
of
the
gallbladder
was
made
.
Despite
being
rare
and
having
a
poor
prognosis
,
hormone-producing
neuroendocrine
tumors
should
be
part
of
the
differential
diagnosis
in
the
approach
of
patients
with
Cushing
's
syndrome
.
Diseases
Validation
Diseases presenting
"large cell neuroendocrine carcinoma of the gallbladder"
symptom
carcinoma of the gallbladder
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