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Signet ring cell carcinoma of the gallbladder: a case report.
[carcinoma of the gallbladder]
Carcinoma
of
the
gall
bladder
is
the
most
common
biliary
tract
tumor
with
higher
incidence
in
females
and
increasing
age
.
The
risk
is
significantly
higher
in
cholelithiasis
.
Signet
ring
cell
carcinoma
is
a
rare
form
of
mucinous
adenocarcinoma
and
has
a
worse
prognosis
.
Early
diagnosis
is
rare
.
We
report
a
case
of
signet
ring
cell
carcinoma
of
the
gall
bladder
in
a
70
years
old
female
patient
.
The
gross
finding
was
yellowish
white
mass
measuring
4
x
3
.
5
cm
on
cut
surface
of
the
gall
bladder
along
with
thickened
wall
.
Histopathological
examination
of
the
specimen
shows
the
sheets
of
signet
ring
cells
with
lateral
spread
through
the
lamina
propria
and
large
amount
of
extracellular
mucin
.
There
was
metastasis
in
the
retroperitoneum
and
mesenteric
lymph
node
.
The
tumor
was
stage
IV
(
according
to
TNM
staging
)
.
Patient
died
20
th
post
operative
day
.
Since
very
few
cases
have
been
reported
,
information
regarding
the
behavior
and
prognosis
of
gall
bladder
carcinoma
is
limited
.
However
it
has
been
seen
that
stage
III
and
IV
carcinoma
usually
have
worse
prognosis
.
Diseases
Validation
Diseases presenting
"early diagnosis"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
adrenomyeloneuropathy
alexander disease
allergic bronchopulmonary aspergillosis
aromatase deficiency
carcinoma of the gallbladder
cholangiocarcinoma
classical phenylketonuria
coats disease
cohen syndrome
congenital adrenal hyperplasia
congenital diaphragmatic hernia
congenital toxoplasmosis
cowden syndrome
cushing syndrome
cutaneous mastocytosis
cystinuria
dentin dysplasia
dentinogenesis imperfecta
dracunculiasis
erdheim-chester disease
erythropoietic protoporphyria
esophageal carcinoma
esophageal squamous cell carcinoma
fabry disease
familial hypocalciuric hypercalcemia
familial mediterranean fever
gm1 gangliosidosis
hirschsprung disease
holt-oram syndrome
homocystinuria without methylmalonic aciduria
hydrocephalus with stenosis of the aqueduct of sylvius
inclusion body myositis
kabuki syndrome
kallmann syndrome
kindler syndrome
krabbe disease
locked-in syndrome
monosomy 21
neuralgic amyotrophy
oculocutaneous albinism
oligodontia
omenn syndrome
oral submucous fibrosis
papillon-lefèvre syndrome
phenylketonuria
primary effusion lymphoma
primary hyperoxaluria type 1
proteus syndrome
pyomyositis
pyruvate dehydrogenase deficiency
scrub typhus
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
thoracic outlet syndrome
triple a syndrome
typhoid
von hippel-lindau disease
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
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