Rare Diseases Symptoms Automatic Extraction
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Resected pleomorphic carcinoma of the gallbladder.
[carcinoma of the gallbladder]
Pleomorphic
carcinoma
is
a
rare
lesion
and
the
literature
contains
few
reports
of
pleomorphic
carcinoma
of
the
gallbladder
.
The
present
study
reports
a
rare
case
of
primary
pleomorphic
carcinoma
of
the
gallbladder
for
which
we
were
able
to
perform
curative
surgery
.
A
77
-
year
-old
woman
with
dementia
developed
nausea
and
anorexia
,
and
computed
tomography
demonstrated
irregular
thickening
of
the
gallbladder
wall
.
Drip
infusion
cholangiography
and
endoscopic
retrograde
cholangiopancreatography
revealed
no
stenosis
of
the
common
and
intrahepatic
bile
ducts
.
We
suspected
carcinoma
of
the
gallbladder
without
lymph
node
metastasis
and
invasion
to
the
common
bile
duct
.
We
guessed
it
to
be
resectable
and
performed
open
laparotomy
.
At
operation
,
the
fundus
of
the
gallbladder
was
adherent
to
the
transverse
colon
,
but
no
lymph
node
and
distant
metastases
were
detected
.
Therefore
,
we
performed
curative
cholecystectomy
with
partial
colectomy
.
Histopathology
and
immunostaining
showed
coexistence
of
an
adenocarcinoma
,
squamous
cell
carcinoma
and
sarcomatous
tumor
of
spindle-shaped
cell
,
as
well
as
transition
zones
between
these
tumors
.
We
diagnosed
stage
I
pleomorphic
carcinoma
of
the
gallbladder
.
No
recurrence
has
been
observed
for
one
and
a
half
years
.
The
biological
behavior
of
pleomorphic
carcinoma
of
the
gallbladder
remains
unknown
.
It
will
be
necessary
to
accumulate
more
case
reports
of
this
tumor
in
order
to
define
diagnostic
criteria
.