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Neuroendocrine tumor of the gallbladder.
[carcinoma of the gallbladder]
Neuroendocrine
tumors
(
NET
)
arise
from
neuroendocrine
cells
and
are
an
exceedingly
rare
malignancy
in
the
gallbladder
.
In
this
case
report
,
a
52
-
year
-old
woman
with
complaints
of
episodic
abdominal
pain
for
two
months
prior
was
admitted
to
our
hospital
.
She
had
no
other
signs
and
symptoms
and
her
laboratory
tests
were
within
normal
limits
.
Ultrasonography
showed
a
broad
-necked
mass
(
26
×
12
mm
)
in
the
gallbladder
for
which
she
underwent
laparoscopic
cholecystectomy
.
The
final
pathological
diagnosis
was
a
high
grade
neuroendocrine
carcinoma
of
the
gallbladder
with
involvement
of
the
lymph
nodes
and
omentum
.
The
patient
received
the
chemotherapy
regimens
of
gemcitabine
plus
cisplatin
,
followed
by
docetaxel
plus
sunitinib
for
her
metastatic
liver
lesions
.
She
also
underwent
radiofrequency
ablation
.
Serial
CT
-scans
revealed
metastatic
liver
lesions
that
had
decreased
in
size
,
with
no
significant
improvement
.
The
patient
refused
additional
treatment
and
at
46
months
,
she
was
doing
well
with
no
complaints
of
any
pain
,
disease
recurrence
,
or
metastatic
progression
.
Diseases
Validation
Diseases presenting
"broad-necked mass"
symptom
carcinoma of the gallbladder
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