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Gallbladder carcinoma with skeletal metastasis in a Nigerian woman: a case report and review of literature.
[carcinoma of the gallbladder]
To
present
a
case
of
skeletal
metastasis
from
a
gallbladder
malignancy
,
a
rare
occurrence
.
A
75
year
old
Nigerian
woman
presented
in
the
surgical
outpatient
clinic
of
the
University
of
Port
Harcourt
Teaching
Hospital
with
a
two
month
history
of
right
hypochondrial
pain
and
three
weeks
swelling
on
the
forehead
.
Physical
examination
revealed
an
ill
looking
,
emaciated
elderly
woman
in
mild
painful
distress
.
She
was
pale
,
afebrile
and
anicteric
.
Skull
x-
ray
revealed
a
well
circumscribed
soft
tissue
mass
over
a
lytic
bone
defect
in
the
frontal
region
.
Abdominal
ultrasound
scan
showed
an
enlarged
gallbladder
with
a
thickened
wall
and
intraluminal
echogenic
mass
,
surrounding
lymphadenopathy
and
intrahepatic
metastasis
.
Radiological
diagnosis
of
advanced
gallbladder
carcinoma
with
both
local
and
distant
metastases
was
made
.
Carcinoma
of
the
gallbladder
with
skeletal
metastasis
is
a
rare
finding
.
However
,
in
any
patient
with
gallbladder
malignancy
distant
metastasis
with
skeletal
involvement
should
be
sought
.
Diseases
Validation
Diseases presenting
"pain"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
adrenomyeloneuropathy
aniridia
aromatase deficiency
carcinoma of the gallbladder
cholangiocarcinoma
coats disease
congenital diaphragmatic hernia
congenital toxoplasmosis
cushing syndrome
cutaneous mastocytosis
cystinuria
dedifferentiated liposarcoma
dentin dysplasia
dracunculiasis
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
erdheim-chester disease
erythropoietic protoporphyria
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
fabry disease
familial mediterranean fever
focal myositis
hirschsprung disease
hodgkin lymphoma, classical
holt-oram syndrome
junctional epidermolysis bullosa
kabuki syndrome
kindler syndrome
lamellar ichthyosis
liposarcoma
locked-in syndrome
lymphangioleiomyomatosis
malignant atrophic papulosis
neuralgic amyotrophy
oligodontia
oral submucous fibrosis
papillon-lefèvre syndrome
phenylketonuria
pleomorphic liposarcoma
primary hyperoxaluria type 1
proteus syndrome
pyomyositis
scrub typhus
sneddon syndrome
systemic capillary leak syndrome
thoracic outlet syndrome
trochlear dysplasia
typhoid
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
wolf-hirschhorn syndrome
This symptom has already been validated