Benign recurrent intrahepatic cholestasis: a long-term follow-up.

[benign recurrent intrahepatic cholestasis]

We report on a case with a 50 -year history of benign recurrent intrahepatic cholestasis , including 33 years of follow-up at our hospital . The attacks of jaundice began at the age of 1 year and have been repeated more than 14 times to date . During the follow-up period at our hospital , the patient has suffered 6 attacks of cholestasis . During the episodes of cholestasis , a dissociation between the serum level of bilirubin and that of bile acids was observed . The analysis of serum bile acids during cholestasis showed that cholic acid and chenodeoxycholic acid were the main bile acids , and no appreciable amounts of the secondary bile acids were detected . Between episodes the liver function tests , including serum bile acids , were normal . Despite multiple attacks of cholestasis over many years , no permanent liver damage has occurred . This case reaffirms the essentially benign nature of this disease .

Diseases
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Diseases presenting "a dissociation between the serum level of bilirubin and that of bile acids was observed" symptom

benign recurrent intrahepatic cholestasis

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