Autosomal-recessive inheritance of benign recurrent intrahepatic cholestasis.

[benign recurrent intrahepatic cholestasis]

Benign recurrent intrahepatic cholestasis (BRIC ) is a rare disorder characterized by recurrent episodes of cholestasis without permanent liver damage . Familial and sporadic cases have been described . Based on existing evidence , both autosomal-recessive and autosomal-dominant inheritance have been considered . We describe a large Dutch pedigree with 4 patients , strongly suggesting autosomal-recessive inheritance .

Diseases
Validation

Diseases presenting "intrahepatic cholestasis" symptom

benign recurrent intrahepatic cholestasis

zellweger syndrome

This symptom has already been validated