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Benign recurrent intrahepatic cholestasis.
[benign recurrent intrahepatic cholestasis]
Benign
recurrent
intrahepatic
cholestasis
is
a
rare
disorder
of
unknown
etiology
and
has
not
yet
been
reported
in
Taiwan
.
We
report
a
case
with
a
typical
clinical
course
.
A
17
-
year
-old
Taiwanese
boy
had
three
episodes
of
pruritus
and
jaundice
from
February
1993
to
July
1995
,
each
lasting
3
to
4
months
.
Jaundice
spontaneously
subsided
and
he
was
symptom-free
during
periods
of
remission
.
A
fourth
episode
of
pruritus
began
in
July
1995
,
with
jaundice
developing
later
and
lasting
for
3
months
.
Laboratory
tests
revealed
direct
hyperbilirubinemia
.
Endoscopic
retrograde
cholangiopancreatography
showed
normal
intra-
and
extrahepatic
biliary
trees
.
Light
microscopy
of
a
liver
biopsy
sample
revealed
hepatocellular
and
canalicular
cholestasis
with
bile
retention
in
the
Kupffer
cells
.
Benign
recurrent
intrahepatic
cholestasis
was
diagnosed
after
exclusion
of
other
possible
causes
of
jaundice
.
The
patient
made
an
uneventful
recovery
.
